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Symptoms, ultrasound imaging and biochemical markers alone or in combination for the diagnosis of ovarian cancer in women with symptoms suspicious of ovarian cancer

Rai, N. and Campaneria, R. and Snell, K. and Mallett, S. and Bayliss, S.E. and Neal, R.D. and Balogun, M. and Kehoe, S. and Deeks, J.K. and Sundar, S. and Davenport, C. (2015) Symptoms, ultrasound imaging and biochemical markers alone or in combination for the diagnosis of ovarian cancer in women with symptoms suspicious of ovarian cancer. Cochrane Library (12). DOI: 10.1002/14651858.CD011964 (In Press)

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Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows: To establish the accuracy of symptoms, ultrasound and biomarkers alone or in combination for the diagnosis of ovarian cancer in pre- and postmenopausal women. To compare the accuracy of different tests or test combinations. We will investigate the following sources of heterogeneity: Population Clinical setting (generalist/primary care/community/family practice) versus specialist setting (cancer unit/cancer centre/gynaecological oncology) Menopausal status Index tests Test positivity threshold Experience of the ultrasound test operator (general sonographers versus specialist interest) Target condition Histological subtype Study quality Case-control versus other study designs Study quality: for study participants not receiving surgery initially following a negative index test result: 12 months follow-up versus less than 12 months follow-up

Item Type: Article
Subjects: Research Publications
Departments: College of Health and Behavioural Sciences > North Wales Centre for Primary Care Research
Date Deposited: 13 Feb 2016 03:12
Last Modified: 13 Feb 2016 03:12
ISSN: 1465-1858
URI: http://e.bangor.ac.uk/id/eprint/6240
Identification Number: DOI: 10.1002/14651858.CD011964
Publisher: Wiley
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