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Single Cell Microdosimetric Studies Comparing Ideal and Measured Nanosecond Pulsed Electric Fields

Denzi, A. and Merla, C. and Palego, C. and Apollonio, F. and Hwang, J.C.M. and Liberti, M. (2013) Single Cell Microdosimetric Studies Comparing Ideal and Measured Nanosecond Pulsed Electric Fields. In: IEEE MTT-S International Microwave Symposium Digest (IMS), Seattle, USA, June 2013.

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Abstract

Recently, the promising effects induced by pulsed electric fields with high intensity and short duration have been highlighted. At the nanosecond time scale, electric pulse targets become both the plasmatic membrane and the sub-cellular structures (possibility of intracellular manipulation). In this paper, a circuit cell model with nucleus is presented, validated and used in order to assess the different cellular and sub-cellular (i.e. nucleus) effects, comparing ideal nanosecond pulsed electric fields (nsPEFs) waveforms with the ones measured from a planar, broadband matched microchamber.

Item Type: Conference or Workshop Item (UNSPECIFIED)
Subjects: Research Publications
Departments: College of Physical and Applied Sciences > School of Electronic Engineering
Date Deposited: 27 Jan 2016 03:36
Last Modified: 27 Jan 2016 03:36
ISSN: 0149-645X
URI: http://e.bangor.ac.uk/id/eprint/6156
Identification Number: DOI: 10.1109/MWSYM.2013.6697655
Publisher: IEEE publishing
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