Genomic islands of speciation separate cichlid ecomorphs in an East African crater lake

Malinsky, M. and Challis, R.J. and Tyers, A.M. and Schiffels, S. and Terai, Y. and Ngatunga, B.P. and Miska, E.A. and Durbin, R. and Genner, M.J. and Turner, G.F. (2015) Genomic islands of speciation separate cichlid ecomorphs in an East African crater lake. Science, 350 (6267). pp. 1493-1498. DOI: 10.1126/science.aac9927

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The genomic causes and effects of divergent ecological selection during speciation are still poorly understood. Here, we report the discovery and detailed characterization of earlystage adaptive divergence of two cichlid fish ecomorphs in a small (700m diameter) isolated crater lake in Tanzania. The ecomorphs differ in depth preference, male breeding color, body shape, diet and trophic morphology. With whole genome sequences of 146 fish, we identify 98 clearly demarcated genomic �islands� of high differentiation and demonstrate association of genotypes across these islands to divergent mate preferences. The islands contain candidate adaptive genes enriched for functions in sensory perception (including rhodopsin and other twilight vision associated genes), hormone signaling and morphogenesis. Our study suggests mechanisms and genomic regions that may play a role in the closely related mega-radiation of Lake Malawi.

Item Type: Article
Subjects: Research Publications
Departments: College of Natural Sciences > School of Biological Sciences
Date Deposited: 17 Nov 2015 02:17
Last Modified: 19 Jan 2016 03:20
ISSN: 0036-8075
Publisher's Statement: This is the author accepted manuscript. The final version is available from AAAS via http://dx.doi.org/10.1126/science.aac9927
URI: http://e.bangor.ac.uk/id/eprint/5849
Identification Number: DOI: 10.1126/science.aac9927
Publisher: American Association for the Advancement of Science (AAAS)
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