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Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA

Mullins, P.G. and McGonigle, D.J. and O'Gorman, R.L. and Puts, N.A.J. and Vidyasagar, R. and Evans, C.J. and Edden, R.A.E. (2014) Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA. NeuroImage, 86. 43–52.

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Abstract

There is increasing interest in the use of edited proton magnetic resonance spectroscopy for the detection of GABA in the human brain. At a recent meeting held at Cardiff University, a number of spectroscopy groups met to discuss the acquisition, analysis and interpretation of GABA-edited MR spectra. This paper aims to set out the issues discussed at this meeting, reporting areas of consensus around parameters and procedures in the field and highlighting those areas where differences remain. It is hoped that this paper can fulfill two needs, providing a summary of the current �state-of-the-art� in the field of GABA-edited MRS at 3 T using MEGA-PRESS and a basic guide to help researchers new to the field to avoid some of the pitfalls inherent in the acquisition and processing of edited MRS for GABA.

Item Type: Article
Uncontrolled Keywords: Biochemistry & Molecular Biology Neuroimaging Neurosciences
Subjects: Research Publications
Departments: College of Health and Behavioural Sciences > School of Psychology
Date Deposited: 09 Dec 2014 16:34
Last Modified: 23 Sep 2015 03:00
ISSN: 1053-8119
URI: http://e.bangor.ac.uk/id/eprint/468
Publisher: Elsevier
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