Iodocyclisations reactions of Boc- and Cbz-protected N-allylguanidines

Al Shuhaiba, Z and Davies, D.H. and Dennis, M. and Evans, D.M. and Fletcher, M.D. and Franken, H. and Hancock, P. and Hollinshead, J. and Jones, I. and Kähm, K. and Murphy, P.J. and Nash, R. and Potter, D. and Rowles, R. (2014) Iodocyclisations reactions of Boc- and Cbz-protected N-allylguanidines. Tetrahedron, 70 ((29)). pp. 4412-4419. DOI: 10.1016/j.tet.2014.03.087

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The cyclisation of mono-protected and bis-protected guanidines 8a�j under standard iodocyclisation conditions (I2/K2CO3) gave the guanidine heterocycles 9�25 via either a direct cyclisation or by a cyclisation/ring-contraction process, which could be controlled by careful selection of conditions.

Item Type: Article
Subjects: Research Publications
Departments: College of Physical and Applied Sciences > School of Chemistry
Date Deposited: 09 Dec 2014 16:31
Last Modified: 23 Sep 2015 02:58
ISSN: 0040-4020
URI: http://e.bangor.ac.uk/id/eprint/362
Identification Number: DOI: 10.1016/j.tet.2014.03.087
Publisher: Elsevier Science
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