The structural and functional diversification of the Toxicofera reptile venom system

Fry, B.G. and Casewell, N.R. and Wüster, W. and Vidal, N. and Young, B. and Jackson, T.N.W. (2012) The structural and functional diversification of the Toxicofera reptile venom system. Toxicon, 60 (4). pp. 434-448. DOI: 10.1016/j.toxicon.2012.02.013

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The evolutionary origin and diversification of the reptilian venom system is described. The resolution of higher-order molecular phylogenetics has clearly established that a venom system is ancestral to snakes. The diversification of the venom system within lizards is discussed, as is the role of venom delivery in the behavioural ecology of these taxa (particularly Varanus komodoensis). The more extensive diversification of the venom system in snakes is summarised, including its loss in some clades. Finally, we discuss the contentious issue of a definition for �venom�, supporting an evolutionary definition that recognises the homology of both the venom delivery systems and the toxins themselves.

Item Type: Article
Subjects: Research Publications
Departments: College of Natural Sciences > School of Biological Sciences
Date Deposited: 09 Dec 2014 16:49
Last Modified: 20 Nov 2015 03:32
ISSN: 0041-0101
URI: http://e.bangor.ac.uk/id/eprint/1186
Identification Number: DOI: 10.1016/j.toxicon.2012.02.013
Publisher: Elsevier
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